Isaac married Abigail Westbrook about 1807 in New York, United States. Abigail (daughter of Westbrook) was born about 1787 in Pennsylvania, United States; died after 1 Oct 1876 in Vassar, Tuscola, Michigan, United States. [Group Sheet] [Family Chart]

1. Anna PARKER was born on 8 Jul 1808 in , Monroe, New York, United States; died on 31 Aug 1908 in Vassar. Tuscola, Michigan, United States.
2. Miles PARKER was born on 27 Dec 1811 in New York, United States; died on 28 Sep 1872 in Vassar, Tuscola, Michigan, United States.
3. Timothy Jeremiah PARKER was born on 13 Sep 1815 in Saratoga Springs, Saratoga, New York, United States; died on 24 Sep 1893 in Vacaville, Solano, California, United States; was buried in Vacaville, Solano, California, United States.
4. John PARKER was born on 20 Jan 1820 in Rochester, Monroe, New York, United States; died on 12 Sep 1912 in Newark, Licking, Ohio, United States; was buried in Cedar Hill Cementary, Newark, Licking, Ohio, United States.